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According to figures released by Worldpanel by Numerator, 6.3% of households now include at least one user, with uptake seeing steep year-on-year climbs (2.3% in 2024 and 4.1% in 2025)

Commercials and celebrities alike are glorifying the benefits of this drug, particularly for its efficacy in facilitating weight loss

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One additional consideration for people on intensive protocols: nausea and reduced fluid intake can sometimes concentrate urine, potentially creating a dilute-adjacent profile that testing sites may flag as a low-validity specimen

Most protocols start with the lowest available dose and increase gradually over weeks to months