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The fact that GLP-1R agonists are sometimes introduced if the patient is intolerant to metformin or metformin is contraindicated, or when patients on metformin are not achieving their HbA1c goals [71] represents essential background information here

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The goal is to improve patient outcomes through a mix of medical and behavioral methods

Within this loop, nutrient stimulation of GIP secretion enhances GLP-1 release [ Figure 1 Section A]

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