GLP-1s are highly effective at controlling blood sugar and slowing down gastric processes, but they are also highly effective (so to speak) at bringing on side effects like constipation, nausea, and abdominal pain that, if untreated, will impact adherence and, in turn, short and long term results
Utilizing the same day of the week, the same time, and noting each injection spot requires only 30 seconds but aids in monitoring rotation and healing
Needle gauges range from 28G to 31G, with 30G and 31G being most comfortable for subcutaneous injection
Although it has been reported that cultured dermal papilla cells expressed VEGF in vitro (3840), we consistently did not detect any upregulation of VEGF mRNA expression in the dermal papilla during the murine hair cycle
Bcl-2 overexpression has been observed in fibroblasts isolated from aged mice with bleomycin-induced lung fibrosis [15], consistent with this mechanism