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Reported observations include: Mild transient drowsiness or fatigue during initial dosing

Prior studies have detected the increased IL-6 when challenged with an intravenous UA solution in healthy volunteers and this variation cannot be reversed by rasburicase which is an effective UA-lowering drug (70)

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8 Development of therapies targeting GST is a major field of research

3.1.2 DHA and cytokines DHA, an n-3 LCPUFA derived from the bioconversion of -ALA, emerges as a crucial regulator of cytokine-driven fibrogenesis