The package inserts for both semaglutide and tirzepatide list a series of warnings and precautions that include thyroid tumors, acute inflammation of the pancreas (pancreatitis), acute gallbladder disease, acute kidney injury (that may stem from dehydration due to excess vomiting or diarrhea), allergic reactions, a heightened risk of bottoming out blood sugars while on blood sugarlowering medications, worsening eye disease for those with type 2 diabetes, an increase in heart rate requiring monitoring, and suicidal thoughts and behaviors
To potentially move them into Category 1 or final Bulks List status, the most effective approach is to present a persuasive case for their clinical efficacy and safety to the Pharmacy Compounding Advisory Committee (PCAC) and submit it to the FDA
Fridays Health is a verified GLP-1 telehealth provider that scores 4.6/5 in our independent review (Top Tier)
Among less frequently assessed adverse events, semaglutide was uniquely associated with increased GERD risk
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