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Ang R, Mastitskaya S, Hosford PS, Basalay M, Specterman M, Aziz Q, Li Y, Orini M, Taggart P, Lambiase PD

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There are conflicting findings regarding changes in the number and function of Treg cells in the gut and circulation of IBD patients

All values were converted to cAMP concentration using cAMP standard curve performed parallel and data were subsequently normalised to the response of 100 M forskolin in each cell line, and then normalised to the WT for each agonist

There is considerable evidence that metabolome changes induced in response to microenvironmental stimuli e.g