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It remains an investigational medicinal product, and therefore there is no official MHRA prescribing information, Summary of Product Characteristics (SmPC), or NICE guidance specific to retatrutide

According to the latest study, there appears to be a strong correlation between hyperselenemia and non-alcoholic fatty liver disease (NAFLD)

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Prolonged exposure to IGF1 LR3 may lead to downregulation of IGF-1 receptors or desensitization of downstream signaling pathways