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In hypothyroidism, reduced thyroid hormone signaling first produces a redox imbalance marked by decreased synthesis of selenoproteins such as glutathione peroxidases and thioredoxin reductases ( In hyperthyroidism, accelerated mitochondrial metabolism produces excessive reactive oxygen species (ROS), overwhelming endogenous antioxidant defenses (114)

For a deeper dive into how the body handles glutathione, see our article on glutathione absorption

Below are some treatments that have proven effective in my practice or shown success in research studies