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It is noteworthy that this superior effectiveness extended to primates (humans and cynomolgus monkeys) and rodent models of obesity and diabetes, such as db/db (diabetic) mice and Zucker diabetic fatty (ZDF) rat

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Eli Lilly has not announced a specific approval submission date, but based on typical trial timelines, an FDA submission could come in 2025 or 2026, with potential approval following 6 to 12 months after that

Tirzepatide, sold as Zepbound for weight management, activates GLP-1 receptors along with receptors for glucose-dependent insulinotropic polypeptide, or GIP, another hormone involved in appetite and blood-sugar regulation