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Many users describe this period as representing a new normal that feels sustainable and genuine

Safety and tolerability are important considerations for any new medication

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However, following the safety concerns raised by rosiglitazone and its potential side effects such as an increased risk of death and MI, [31] the Food and Drug Administration (FDA) mandated that innovative antidiabetic therapies for T2D be scrutinized by conducting safety trials to confirm their CV neutrality

10.1186/s13229-015-0010-7 [DOI] [PMC free article] [PubMed] [Google Scholar] 33.Politi P, Cena H, Comelli M, Marrone G, Allegri CE, Emanuele E, et al