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Assessment of -amyloid protein, neurotropic markers, purinergic and cholinergic activities in hippocampus tissues Enzyme-linked immunosorbent assays (ELISA) were used to quantify several neural biomarkers in hippocampal tissue homogenates, including brain-derived neurotrophic factor (BDNF), insulin-like growth factor-1 (IGF-1), glycogen synthase kinase-3 beta (GSK3), beta-site amyloid precursor protein cleaving enzyme 1 (Bace1), adenosine triphosphatase (ATPase), adenosine deaminase (ADA), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE)
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Besouw MT, Bowker R, Dutertre JP, Emma F, Gahl WA, Greco M, Lilien MR, McKiernan J, Nobili F, Schneider JA, Skovby F, van den Heuvel LP, Vant Hoff WG, Levtchenko EN (2011) Cysteamine toxicity in patients with cystinosis