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it has been tied to delta-wave EEG activity, neurotransmitter changes, motor recovery in rat stroke models, and HPA-axis signaling

One of the primary reactions of methylcobalamin in the body is to convert homocysteine to methionine high homocysteine levels are undesirable and known to be an indicator of heart disease and stroke risk due to the fact free homocysteine in the blood causes sclerosis of the arteries, putting strain on the vascular system and the heart

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- At 1 month, no significant improvement in phantom limb pain was observed compared to sham treatment