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Supports Circadian Rhythm Research Because of its connection to sleepwake cycles, DSIP is widely used in studies examining circadian rhythm alignment

Excipients in formulations may occasionally trigger sensitivity reactions in some individuals

Other studies confirmed that continuous afferent vagal stimulation reduces inflammatory neuroglia in the SN, upregulates rate-limiting enzyme density in the LC, and alleviates motor deficits in PD rat models (111)

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Common mild side effects include injection-site irritation or temporary water retention, but serious reactions warrant immediate protocol adjustment or discontinuation