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A 2025 Nature Medicine study of 200,000+ patients found: 2.02.5x higher risk of drug-induced pancreatitis Higher incidence of kidney stones and arthritis Chronic pancreatitis can permanently damage the pancreas and raises long-term cancer risk

Those taking multiple medications should check for interactions with their pharmacist or doctor

The idea of how it works is that it helps grow new tiny blood vessels in healing tissue, nudges growth signals where you are hurt, and plays with the nitric-oxide system that matters for both the gut and blood vessels

These trials were specifically monitored for cancer-related adverse effects and found no notable differences in thyroid cancer incidence between the treatment and control groups

The problems arise when unverified clinics use substandard products, incorrect dosages, or untrained staff