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Injectable and earlier oral GLP-1 drugs such as semaglutide are peptide molecules: chains of amino acids that closely resemble the body's own glucagon-like peptide-1 hormone

At the higher weight loss dose of 2.4 mg weekly, semaglutide reduced MACE by 20% (HR 0.80, p less than 0.001) and all-cause mortality by 19%

Consequently, as life expectancy increases and the baby-boom generation reaches retirement age, the already heavy burden imposed by ESRD on the US health care system is set to increase dramatically

But younger women, ages 30 to 49, are twice as likely than men to have used them

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