Fasting induces a metabolic shift from glucose utilization to fatty acid oxidation and ketone body production as primary energy sources
These therapeutic effects correlated with preservation of both blood and spinal cord GSH levels in comparison to untreated transgenic controls, indicating that Immunocal is able to act directly on the CNS to preserve GSH status in the context of neurodegenerative disease
Oral administration of AC in rotenone-induced PD rat models resulted in a significant decrease in the expressions of both -synuclein and caspase-3, while also elevating the expression of MAP2, a protein essential for neuronal structure and survival, in the SN
172 PROM2 regulates endocytosis, and its overexpression leads to significant changes in plasma membrane organization and function, including increased cellular pseudopodia, which has invasive potential and is a potential biomarker for predicting distant metastasis and decreased survival
Addressing these questions is essential for deciphering LC cell survival strategies and developing targeted therapies that exploit this dynamic interplay
