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This function is defective in type 2 diabetes [7,8,9], presumably because DPP-4 activity is enhanced in patients with glucose intolerance [9,10,11]

For maintenance therapy without neurological involvement, 1 mg is given every 3 months

Citrulline malate, on the other hand, blends citrulline with malic acid

Conversely, some patients opt for evening or nighttime administration, particularly if they experience gastrointestinal side effects such as nausea

Involuntary muscle contractions occur when muscles lack adequate potassium (3,500mg daily), calcium (1,000mg daily), or magnesium (400mg daily)deficiencies commonly seen with dehydration or excessive sweating