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Results maintenance requires ongoing or periodic use - stopping treatment leads to gradual regression over 2-6 months as new collagen formation stops and natural aging resumes

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Overall, further clinical trials in humans are necessary to demonstrate that dietary interventions can simultaneously influence the microbiome, intestinal permeability, inflammation, and neurocognitive symptoms, making them a compelling complementary strategy in the treatment of ME/CFS [10, 11, 13]

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Laboratory Handling and Storage Protocols Lyophilized Powder Storage: Store at -20C to -80C in original sealed vial Protect from light exposure and moisture Desiccated storage environment recommended Stability data available for 24+ months at -20C Stability Considerations: Ipamorelin demonstrates excellent stability as a lyophilized powder due to its synthetic amino acid modifications providing protease resistance