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Vitamin B12 supplementation in metabolic health

[73] As noted above, the completely synthetic laboratory synthesis of B 12 was achieved by Robert Burns Woodward and Albert Eschenmoser in 1972, though this process has no commercial potential, requiring more than 70 steps and having a yield well below 0.01%

Intrinsic factor binds to vitamin B12, so that you can absorb it into the blood

The excess of this vitamin is excreted in the urine, and it has a longer half-life compared to Butaphosphan due to its storage in the liver and its role in long-term metabolic functions

Additionally, older adults who naturally have a more challenging time absorbing vitamin B12 or those on certain medications that affect B12 absorption may be ideal candidates