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CagriSema combines two separate molecules (an amylin analog plus a GLP-1 agonist)

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Do not store tirzepatide in the freezer, and do not use pens that have been frozen, even if subsequently thawed

In 1891, it was found to be useful to treat malaria, thus making methylene blue "the first synthetic compound ever used as an antiseptic in clinical therapy and the first antiseptic dye to be used therapeutically," according to the authors of a Medicinal Research Reviews paper on the compound