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Layering on requirements for optimal pharmacological profiles and drug-like properties to support oral dosing adds another level of complexity. But acording to Terry Kenakin, a former GSK drug developer now at the University of North Carolina-Chapel Hill in the US, we are in what I call a renaissance in terms of finding compounds that modify the function of these [GPCR receptors]

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In general, a dietary carotenoid concentration of between 50 and 100 mg/kg feed is sufficient to generate an optimal pigmentation level after one month in the shrimps body