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30,31 In addition, mitochondrial oxidative stress may also trigger the phosphorylation of glycogen synthase kinase-3 (GSK-3), which activates the mixed lineage kinase 3 (MLK3) protein

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Vitamin B 12 deficiency results in megaloblastic anemia, GI lesions, and neurologic damage that begins with an inability to produce myelin and is followed by gradual degeneration of the axon and nerve head

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By potentially downregulating TGF-1, AHK-Cu may alter these cellular processes, possibly affecting cell growth and the immune response at a cellular level