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Methodological caveat: Most human trials use combination formulations published studies often combine GHK-Cu with other actives (e.g., retinoids, vitamin C), making it difficult to isolate GHK-Cus independent contribution

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These differences in duration can impact convenience, side effects, and how the medication fits into a broader weight management plan

Instead, the focus should be on reducing avoidable triggers for shedding

Clinical trials also show that some lean mass loss occurs during weight reduction with GLP-1 medications