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Additionally, tirzepatide may cause fewer gastrointestinal side effects and provides extra benefits for patients with type 2 diabetes or increased cardiovascular risk, including improved glucose control and reduced cardiovascular event risk

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However, sustained changes in acylcarnitine metabolism could disrupt mitochondrial function and energy homeostasis, contributing to muscle wasting, fatigue, reduced physiological resilience, and conditions like insulin resistance and diabetes (Batchuluun et al., 2018