can semaglutide effect period Pfizer pushes ahead with trial for once-a-day weight-loss pill Wegovy (semaglutide) Weight Loss Injection

Toxicol Pathol 25, 24555

Abstract Medical therapeutics for weight loss are changing the landscape of obesity but impacts on obesity-associated cancer remain unclear

Interestingly, GLP-1RAs are known to reduce appetite and food intake partly via appetite-inhibitory neurotransmission signaling within the arcuate nucleus [16, 17], possibly resulting in subsequent improvements in insulin resistance and serum lipid profiles (e.g., reduction in triglyceride levels)

Saleh, J., Peyssonnaux, C., Singh, K

Combined with potential GI side effects, this may lead to fluid and electrolyte loss, making intentional hydration more important