Both medications can play a valuable role in weight management, but they work best when paired with long-term lifestyle changes like balanced eating and regular movement
From my conversations with patients, we often solve early hurdles with a short troubleshooting plan: small dietary tweaks during dose increases, antinausea strategies when needed, and phone checkins with the clinic
IGF binds to its cell surface receptors such as type I insulin-like growth factor receptor (IGF-IR) and then initiates multiple signaling pathways including PI3K/Akt, MAPK, JAK/STAT, Src, and focal adhesion kinase (FAK), which act in concert to stimulate cancer cell proliferation, survival and migration
Fat is one option (yay!), but muscle is another (boo!)
Int J Cancer 118(7):16531659 Puzianowska-Kuznicka M, Krystyniak A, Madej A et al (2002) Functionally impaired TR mutants are present in thyroid papillary cancer