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Human apo-lactoferrin as a physiological mimetic of hypoxia stabilizes hypoxia-inducible factor-1 alpha

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The relative contribution of each receptor target (GIPR, GLP-1R, GCGR) to the effects reported in human trials remains a mechanistic priority, because receptor-selective dissection studies in humans have not appeared in the primary literature

These medications may indirectly improve insulin sensitivity through weight loss and improved glycaemic control