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But their biggest impact may not be treating a subset of OSA patientsit may be forcing the field to look beyond weight

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Others have suggested that complement deposition on parasite membranes leads to assembly of membrane attack complex (MAC) that triggers Ca 2+ influx/overload, disruption of mitochondrial membrane potential, increase in mtROS production, and release of mitochondrial molecules into cytosol, thus signaling apoptosis and parasite death (Irigon et al., 2009)