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Conflicts of Interest Author Lew Lim is the Founder & CEO of Vielight Inc., a manufacturer of photobiomodulation devices

Studies show FOXO4-DRI treatment reduces senescent cell markers including p16, p21, and senescence-associated -galactosidase activity by over 50% in expanded human chondrocytes at population doubling level 9 (PDL9), the stage typically used for clinical implantation

doi: 10.1038/s41586-020-2338-1 2

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Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival