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The trials main goal, though changing the rate at which the brain metabolizes glucose was not met, which researchers suggested could have been a result of its small size

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95% CI, 1.03-1.07)

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In mouse models of type 2 diabetes induced by a highfat diet and streptozotocin, 4 weeks of 5amino1mq injection reduced fasting blood glucose by 25%30%, increased insulin secretion by over 20%, and significantly decreased cell apoptosis

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PMID 18158646

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The tirzepatide label recommends a backup method for 4 weeks after starting and after each dose increase, since gastric emptying is most delayed right after a dose change

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