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NOCA4 attaches to ferritin and is destroyed by ferritin phagocytosis (76), eventually releasing free iron to participate in the Fenton reaction, which generates ROS and increases the accumulation of intracellular lipid peroxides (LPOs) and ferroptosis (77) ( Figure 2 )

The sustained opening of mPTP leads to loss of mitochondrial function, which ultimately triggers apoptosis or necrosis and exacerbates tissue damage

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Do you need a prescription for glutathione injections