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As we age, our natural glutathione levels decline, which is partly why skin can appear duller and more prone to hyperpigmentation over time

This makes the lowest dose conveniently equal to the smallest easily-measured volume on an insulin syringe

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The saline + Laser and PDA@Pt + Laser groups were subjected to laser irradiation (808 nm, 1 W/cm 2 , 5 min) 12 and 24 h after administration