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In a large retrospective analysis of patients with T2DM who had received GLP-1 based therapy (n = 461,382), over 20 % of patients had nutritional deficiencies diagnosed within one year of starting treatment, with Vitamin D deficiency the most common (14 % of patients at one year), and 3 % of patients were diagnosed with muscle loss within one year [69]
Yes and not only because of weight loss
Target serum levels of 40-60 ng/mL
Retatrutide shows none of these characteristics
The SUSTAIN-6 trial examined the effect of once-weekly semaglutide (0.5 or 1 mg) on cardiovascular outcomes in people with type 2 diabetes and again showed a favourable effect on cardiovascular events compared with placebo [26]
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