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The solution is cooled to about 1C (-2 to 4C) and p -toluenesulfonyl chloride (1.0 kg) is added and then triethylamine (0.82 kg) at no more than 10C is slowly added (over about 3-6 hours in an exothermic reaction)

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Its ability to cross cellular membranes and interact with various molecular targets makes it potent in managing oxidative stress and inflammatory responses

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Regarding iron metabolism, the iron chelator deferoxamine mesylate can treat experimental uveitis in Lewis rats, resulting in a significant reduction in choroidal inflammation and retinal damage [319]