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Systemic administration (injectable or oral), which is less common than topical use and not part of approved or standard applications, would theoretically carry different safety considerations requiring appropriate clinical evaluation, though limited research on parenteral administration in animals has suggested acceptable safety profiles at moderate doses

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Yes, when used correctly

Eur J Clin Nutr 72, 105111.CrossRefGoogle ScholarPubMed Gandek, TB, van der Koog, L & Nagelkerke, A (2023) A comparison of cellular uptake mechanisms, delivery efficacy, and intracellular fate between liposomes and extracellular vesicles

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