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Trajectory A indicated maturation, ending in CD4 T central memory/regulatory cells, whereas Trajectory B indicated proliferation, terminating in CD4 T-dividing cells

The same ligand also showed the highest binding energy (-9.845 Kcal/Mol) when docked with PPARG (pdb id-1FM9) and formed three H-bond with Histidine (HIS) 323, Serine (SER) 289, HIE 449 residues and several hydrophobic, and polar interactions (Supplementary Table S11)

Nrf2 further plays a role in regulating the regeneration of the redox electron donor NADPH