and notwithstanding the limited evidence (5), this remains the first-line pharmacotherapy in the management of BAD (6)
And people who stopped using the medications were significantly less optimistic about their benefits: Only about half of those who had used injectable weight-loss drugs in the past said they were effective, compared with nearly three-quarters of those who were actively using the treatments
Likewise, in preclinical models, GIP-GLP-1 co-agonist has also showed the same phenomena in mice [56]
In this review, we systematically synthesizes current knowledge on BA-gout interactions, elucidated how BA disturbances exacerbate disease progression, discussed the factors contributing to metabolic disorders of BAs, and evaluated promising therapeutic strategies targeting BA pathways
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