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The receptor-mediated transport systems are the most investigated for targeting nanoparticles, the surface of the majority of nanosystems is coupled with BBB receptor ligands

Expression of apoptosis related proteins in brains of patients with Alzheimer's disease

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By contrast, preclinical in vivo and in vitro studies both indicate that incretin receptor agonism can attenuate fibrogenic signalling in models of kidney disorders, and thus the positive clinical trial data on kidney function outcome measures may, in part, be mediated by inhibition of fibrosis

doi:10.1007/s10620-009-0854-9 Liu JH, Chen GH, Yeh HZ, Huang CK, Poon SK