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Liposomal formulations improve nutrient absorption compared to standard capsules by encapsulating the molecule in a lipid layer, but their bioavailability still falls well short of that of intravenous delivery

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Furthermore, the Safety of Care RFI included in the CY 2025 OPPS/ASC Proposed Rule (89 FR 94514 through 94521) provided the public with information about potential methodology updates that were being considered by CMS