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The future of GLP-1RAs in anti-inflammatory therapy looks promising, with ongoing research aiming to optimize their therapeutic use, develop patient-specific treatment paradigms, and explore novel applications

GLP-1 drugs can also contribute to weight loss, and some of these drugs, including Ozempic, have been approved as weight loss medications because of their ability to make people feel full for a longer period of time

This is the phase where the semaglutide plateau becomes a common concern, and it is where many researchers either adjust their approach or lose motivation

Three further Phase 3 trial results in the TRIUMPH programme are due before the end of 2026: TRIUMPH-2 in obesity with type 2 diabetes, TRIUMPH-3 in obesity with established cardiovascular disease (with further safety information relevant to higher-risk populations), and obstructive sleep apnoea

Most people notice appetite changes in 13 weeks and weight loss soon after