Note: As of January 2023, Modifier JZ was introduced to attest that there was zero drug wastage, and at least one of these modifiers (JW or JZ) is now required on all applicable Medicare drug claims
[DOI] [PubMed] [Google Scholar] 9.Sikiric P., Seiwerth S., Rucman R., Kolenc D., Vuletic L.B., Drmic D., Grgic T., Strbe S., Zukanovic G., Crvenkovic D., et al
The rationale is that localized delivery concentrates the compound at the target tissue, potentially increasing efficacy relative to systemic dose
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