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Description

Glucagon receptor activation stimulates hepatic glucose production, increases hepatic lipid oxidation and fatty acid beta-oxidation, and promotes thermogenesis and energy expenditure

This creates a 5mg/mL concentration where a 1mg starting dose requires 20 units (easy to read on any syringe) and a 2mg dose requires 40 units (clean, precise marking)

Mulvihill, E

To overcome this limitation, various modifications and delivery strategies to enhance the pharmacokinetic properties and therapeutic efficacy of GLP-1 analogs have been studied