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This simple preventive step addresses a modifiable risk factor without requiring dose adjustment or discontinuation of semaglutide or other GLP-1 compounds

Manufacturer guidance and lactation studies have not established clear safety profiles for these medications in breastfeeding populations, which means the medications are typically not recommended during nursing without explicit medical supervision

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Based on clinical findings, the diagnostic hypotheses included melanotic macula, melanoma, fixed pigmented erythema, and postinflammatory hyperpigmentation