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STZ increased the serum IL-6 level, while PRAM and LIRA restored its normal level There was a dramatic decrease in the level of the inflammatory marker, IL-6 level after PRAM and LIRA treatment

Briefly, we reviewed the type and strength of the available evidence (level) and used the study reference(s) that provided the highest level of evidence to formulate each specific recommendation

The peptide was first isolated during experiments in rabbits and named for its reported association with increased electroencephalographic delta activity

AA: Data curation, Writing review & editing

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