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Whilst most skin changes during Ozempic treatment are likely to be mild and manageable, certain situations warrant prompt medical attention

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Patients who lost 1130% of their body weight, the range most commonly associated with GLP-1 medications, frequently report loose skin after GLP-1 treatment concentrated around the abdomen, upper arms, and inner thighs

The effect was most pronounced for old RBC when experimentally evoked by a hyperosmotic shock, such that PS exposure increased 10-fold by 4 weeks storage and more so in old RBC (Bosman et al., 2011)