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Plasma concentrations of GHK decline with age, from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60

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Stimulating this receptor both triggers GH release directly and suppresses somatostatin's inhibitory tone, effectively releasing two brakes at once

Mol Asp Med 30:112 Foyer CH, Halliwell B (1976) Presence of glutathione and glutathione reductase in chloroplasts proposed role in ascorbic-acid metabolism