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Consequently, once-daily subcutaneous administration of liraglutide 3.0 mg was developed for the treatment of obesity [21] and once-weekly subcutaneous administration of semaglutide 2.4 mg is currently being investigated in phase III trials for this indication [22]

Overall, 6 out of 13 patients prematurely discontinued the study, all of them because of an AE (lipase increased, pyelonephritis, Grade 2 discomfort, constipation, nausea, presyncope)

10.1093/jnci/djy090 82 ShenY.ChenG.ZhuangL.XuL.LinJ.LiuL

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