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The Phase 2 data showed slow titration cut GI adverse events by approximately 50% (Rosenstock et al., Lancet, 2023)

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GLP-1 agonists work best when combined with healthy lifestyle changes, including diet and exercise

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Liu Z, Iyer MR, Godlewski G et al (2021) Functional selectivity of a biased cannabinoid-1 receptor (CB 1 R) antagonist

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Phase 3 trials (large human trials with thousands of participants) are still running, and Lilly plans to apply for regulatory approval once the TRIUMPH programme publishes its results across 2026

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