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chronic weight management is more variable, often BMI-gated, and sometimes excluded

Nevertheless, Neeland and his colleagues concluded that the available evidence suggests that the proportion of lean and muscle mass people lose while taking GLP-1s is in line with the proportion that people lose through diet and exercise alone, but called for additional research to confirm

"There's not really any evidence for efficacy, the Cleveland Clinic's Nissen said

Long-term effectiveness data over a 1-year follow-up period are a key strength of the study, given the relatively recent approval of tirzepatide

Frequently Asked Questions Are GLP-1 medications contraindicated in Crohn's disease