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Its ability to normalize keratinocyte differentiation and regulate inflammation makes it a valuable systemic option, particularly for patients unable to afford biologic therapies (Natsis et al

Single-cell profiling has identified microglia as key sentinel cells of the gutbrain axis that respond rapidly to intestinal inflammatory cues [13]

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Confirmed at 28 days A follow-up 28-day study (Babula et al., 2024) extended the finding: 5-Amino-1MQ dose-dependently limited body weight and fat mass gain without changing food intake, and it improved liver markers in obese mice